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Brian Sweet, BS Pharm, MBA

Executive Director, Health Economics & Outcomes Research
Geron
Naples, FL


Brian Sweet

Brian is an innovative, executive Real World Evidence and scientific evaluation leader with vision and extensive experience in directing clinical pharmacy programs and managing strategic business initiatives which provide high impact. Over 28 years of combined managed care, pharmacy benefit management (PBM), pharmaceutical market access/research (primary care products, biologics, and oncology agents), and senior healthcare executive experience. He has expert knowledge in health technology assessment and critical appraisal, evaluation and design of comparative effectiveness and observational studies, value assessment frameworks, and total cost-of-care management with an emphasis on patient-oriented outcomes. In 2013, Brian was named the No. 3 influencer in evidence development by HealthNetwork Communications.

Prior to joining Geron as the Executive Director, Health Economics & Outcomes Research, Brian was the Head of Real World Evidence Capabilities & Innovation at Bristol Myers Squibb (BMS), where he led global RWE strategy and partnerships with payers and providers across oncology, hematology, cardiovascular, and immunology. His leadership resulted in securing real-world data partnerships that demonstrate product value and enhance market access. Notably, he has designed integrated data sets across several therapeutic areas for longitudinal RWE and outcomes research collection to demonstrate total cost of care savings with costly medications.

In his previous role, Brian was the Executive Director of Health Economics & Outcomes Research (HEOR) Oncology, where he led and managed the US HEOR Oncology organization at Bristol-Myers Squibb. In this role, he oversaw all Health Economic & Outcomes Research team, worked with external collaborative RWE research partners, and focused on value, access, and heath technology assessment needs for the portfolio.

Before joining Bristol-Myers Squibb, Brian was the Executive Director of US Payer & Real World Evidence at AstraZeneca where he led the US initiative in Real World Evidence (RWE) and comparative effectiveness research collaborating with health plans, pharmacy benefit managers, and a variety of key business partners. He developed and oversaw the Health Economics and Outcomes Research team which focused on the development and implementation of US-based HEOR and RWE studies. In addition, he coordinated with managed markets customers on the development of performance-driven models, health improvement programs, value-based insurance designs, value assessment framework evaluations, and evolving healthcare reform issues.

Sweet was also the Chief Pharmacy Officer at WellPoint from 1995 to 2010, a 34 million member health benefits company located in Indianapolis, Indiana. He was responsible for overseeing all Clinical Pharmacy Services at WellPoint including leading the National Pharmacy and Therapeutics Committee, which uses integrated data analyses and total cost of care modeling to improve patient health outcomes. He also provided strategic leadership to establish enterprise pharmacy programs as an integral part of the organization in developing corporate pharmacy policy and innovative pharmacy benefit designs.

Brian earned his Bachelor’s of Science degree in Pharmacy from the State University of New York at Buffalo School of Pharmacy in 1988 and his Master’s degree in Business Administration from SUNY Buffalo School of Management in 1994.

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